Estrogen Balance in Men

Reference

1. Pavlovich CP, King P, Goldstein M, Schlegel PN. Evidence of a treatable endocrinopathy in infertile men. J Urol. 2001;165:837–41.

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   Evidence of a treatable endocrinopathy in infertile men

   The study titled “Evidence of a treatable endocrinopathy in infertile men” by Pavlovich CP, King P, Goldstein M, and Schlegel PN, published in the Journal of Urology in 2001, discusses the presence of a potentially treatable endocrinopathy (a hormonal disorder) in infertile men.

   The authors present evidence that certain hormonal imbalances may contribute to male infertility. They likely explore diagnostic and treatment options for these hormonal disorders, which could potentially improve the fertility of affected men. However, without access to the full text of the article, it is not possible to provide a detailed summary of the specific findings and recommendations made by the authors.

   For more details visit at https://www.sciencedirect.com/science/article/pii/S0022534705665408

2. Luboshitzky R, Kaplan-Zverling M, Shen-Orr Z, Nave R, Herer P. Seminal plasma androgen/oestrogen balance in infertile men. Int J Androl. 2002;25:345–51.

   View Summary +

   Seminal plasma androgen/oestrogen balance in infertile men

   The study titled “Seminal plasma androgen/oestrogen balance in infertile men” by Luboshitzky R, Kaplan-Zverling M, Shen-Orr Z, Nave R, and Herer P, published in the International Journal of Andrology in 2002, investigates the androgen (male sex hormones) and oestrogen (female sex hormones) balance in the seminal plasma of infertile men.

   The authors likely explore the hormonal composition of seminal fluid in infertile men and its potential impact on fertility. They may have assessed whether an imbalance in androgen and oestrogen levels within seminal plasma could be associated with male infertility.

   For more details visit at https://onlinelibrary.wiley.com/doi/abs/10.1046/j.1365-2605.2002.00376.x

3. Dostalova P, Zatecka E, Dvorakova-Hortova K. Of Oestrogens and Sperm: A Review of the Roles of Oestrogens and Oestrogen Receptors in Male Reproduction. Int J Mol Sci. 2017;18(5):904. Published 2017 Apr 25. doi:10.3390/ijms18050904.

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   Dvorakova-Hortova K. Of Oestrogens and Sperm

   The review article titled “Of Oestrogens and Sperm: A Review of the Roles of Oestrogens and Oestrogen Receptors in Male Reproduction” by Dostalova P, Zatecka E, and Dvorakova-Hortova K, was published in the International Journal of Molecular Sciences in 2017. This review focuses on the roles of oestrogens (estrogens) and oestrogen receptors in male reproduction.

   For more details visit at https://www.mdpi.com/1422-0067/18/5/904

4. Giwercman A. Estrogens and phytoestrogens in male infertility. Curr Opin Urol. 2011;21(6):519-26.

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   Estrogens and phytoestrogens in male infertility

   The article titled “Estrogens and phytoestrogens in male infertility” by Giwercman A, published in Current Opinion in Urology in 2011, delves into the impact of estrogens and phytoestrogens on male fertility. It discusses the presence of low levels of estrogens in males, their physiological roles in male reproduction, and how elevated estrogen levels or exposure to environmental estrogens may affect male fertility. Furthermore, the article explores the influence of phytoestrogens, which are estrogen-like compounds found in certain foods and supplements, on male reproductive parameters and hormone balance, shedding light on the complex relationship between these compounds and male infertility.

   For more details visit at https://journals.lww.com/co-urology/FullText/2011/11000/Estrogens_and_phytoestrogens_in_male_infertility.15.aspx

5. Leavy M, Trottmann M, Liedl B, et al. Effects of Elevated β-Estradiol Levels on the Functional Morphology of the Testis – New Insights. Sci Rep. 2017;7:39931. Published 2017 Jan 3. doi:10.1038/srep39931.

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   Effects of Elevated β-Estradiol Levels on the Functional Morphology of the Testis – New Insights

   The study titled “Effects of Elevated β-Estradiol Levels on the Functional Morphology of the Testis – New Insights” by Leavy M, Trottmann M, Liedl B, et al., was published in Scientific Reports in 2017. This study explores the impact of elevated levels of β-estradiol (a type of estrogen) on the functional morphology of the testis. The research likely investigates how increased β-estradiol levels affect the structure and function of the testes, offering new insights into the potential effects of estrogen on male reproductive physiology. For a more detailed examination of the findings and insights, you can access the full article via the original publication in Scientific Reports, Volume 7, published on January 3, 2017, with the DOI: 10.1038/srep39931, which is available through academic databases or the journal’s website.

   For more details visit at https://www.nature.com/articles/srep39931

6. Gülkesen K. H., Erdoğru T., Sargin C. F. & Karpuzoğlu G. Expression of extracellular matrix proteins and vimentin in testes of azoospermic man: an immunohistochemical and morphometric study. Asian J. Androl. 4, 55–60 (2002).

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   Expression of extracellular matrix proteins and vimentin in testes of azoospermic man: an immunohistochemical and morphometric study

   The study titled “Expression of extracellular matrix proteins and vimentin in testes of azoospermic man: an immunohistochemical and morphometric study” by Gülkesen K. H., Erdoğru T., Sargin C. F., and Karpuzoğlu G. was published in the Asian Journal of Andrology in 2002. This study likely involves an investigation into the expression of extracellular matrix proteins and vimentin in the testes of azoospermic men, employing immunohistochemical techniques and morphometric analysis. The research may aim to understand the role of these proteins in testicular function and provide insights into the pathophysiology of azoospermia, a condition characterized by the absence of sperm in the semen. For a more detailed examination of the study’s findings and methods, you can access the full article in the Asian Journal of Andrology, Volume 4, pages 55–60, published in 2002. Please note that you may need access through an academic database or the journal’s website to read the complete article.

   For more details visit at https://www.researchgate.net/profile/Kemal-Guelkesen/publication/11455979_Expression_of_extracellular_matrix_proteins_and_vimentin_in_testes_of_azoospermic_man_An_immunohistochemical_and_morphometric_study/links/00b4952dd0fbd282d9000000/Expression-of-extracellular-matrix-proteins-and-vimentin-in-testes-of-azoospermic-man-An-immunohistochemical-and-morphometric-study.pdf

7. Santamaria L., Martinez-Onsurbe P., Paniagua R. & Nistal M. Laminin, type IV collagen, and fibronectin in normal and cryptorchid human testes. An immunohistochemical study. Int. J. Androl. 13, 135–46 (1990).

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   Laminin, type IV collagen, and fibronectin in normal and cryptorchid human testes. An immunohistochemical study

   The study titled “Laminin, type IV collagen, and fibronectin in normal and cryptorchid human testes: An immunohistochemical study” by Santamaria L., Martinez-Onsurbe P., Paniagua R., and Nistal M. was published in the International Journal of Andrology in 1990. This research likely involves an immunohistochemical analysis of the presence and distribution of laminin, type IV collagen, and fibronectin in both normal and cryptorchid (undescended testes) human testes. The study likely aims to explore the role of these extracellular matrix components in testicular development and function, especially in the context of cryptorchidism. For a more detailed understanding of the study’s findings and methodologies, you can access the full article in the International Journal of Andrology, Volume 13, pages 135–146, published in 1990, through academic databases or the journal’s website.

   For more details visit at https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-2605.1990.tb00970.x

8. Martin R., Santamaría L., Nistal M., Fraile B. & Paniagua R. The peritubular myofibroblasts in the testes from normal men and men with Klinefelter’s syndrome. A quantitative, ultrastructural, and immunohistochemical study. J. Pathol. 168, 59–66 (1992).

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   The peritubular myofibroblasts in the testes from normal men and men with Klinefelter’s syndrome. A quantitative, ultrastructural, and immunohistochemical study

   The study titled “The peritubular myofibroblasts in the testes from normal men and men with Klinefelter’s syndrome: A quantitative, ultrastructural, and immunohistochemical study” by Martin R., Santamaría L., Nistal M., Fraile B., and Paniagua R. was published in the Journal of Pathology in 1992. This research appears to involve a comprehensive investigation into the peritubular myofibroblasts present in the testes of both normal men and men with Klinefelter’s syndrome. The study likely utilizes quantitative, ultrastructural, and immunohistochemical methods to examine the characteristics and distribution of these myofibroblasts. The goal may be to gain insights into how peritubular myofibroblasts contribute to testicular structure and function, particularly in the context of Klinefelter’s syndrome, a genetic condition associated with male infertility. For a more detailed understanding of the study’s findings and methodologies, you can access the full article in the Journal of Pathology, Volume 168, pages 59–66, published in 1992, through academic databases or the journal’s website.

   For more details visit at https://pathsocjournals.onlinelibrary.wiley.com/doi/abs/10.1002/path.1711680111

9. Hess RA, Bunick D, Lee KH, et al. A role for oestrogens in the male reproductive system. Nature. 1997;390(6659):509-12.

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   A role for oestrogens in the male reproductive system

   The study titled “A role for oestrogens in the male reproductive system” by Hess RA, Bunick D, Lee KH, et al. was published in the journal Nature in 1997. This research likely presents evidence and findings suggesting that oestrogens (estrogens), typically considered female sex hormones, play a role in the male reproductive system. The study may have explored the physiological functions of oestrogens in males, potentially focusing on their impact on testicular development, spermatogenesis, and other aspects of male reproductive health. For more detailed information and a comprehensive understanding of the study’s findings, you can access the full article in Nature, Volume 390, Issue 6659, pages 509-512, published in 1997, through academic libraries, databases, or the journal’s website.

   For more details visit at https://www.nature.com/articles/37352

10. Luboshitzky R, Kaplan-zverling M, Shen-orr Z, Nave R, Herer P. Seminal plasma androgen/oestrogen balance in infertile men. Int J Androl. 2002;25(6):345-51.

    View Summary +

    Seminal plasma androgen/oestrogen balance in infertile men

    The study titled “Seminal plasma androgen/oestrogen balance in infertile men” by Luboshitzky R, Kaplan-Zverling M, Shen-Orr Z, Nave R, and Herer P was published in the International Journal of Andrology in 2002. This research likely investigates the balance between androgens (male sex hormones) and oestrogens (female sex hormones) in the seminal plasma of infertile men. The study may aim to understand how this hormonal balance or imbalance may be related to male infertility. For more detailed information and a comprehensive understanding of the study’s findings, you can access the full article in the International Journal of Andrology, Volume 25, Issue 6, pages 345-351, published in 2002, through academic libraries, databases, or the journal’s website.

    For more details visit at https://onlinelibrary.wiley.com/doi/abs/10.1046/j.1365-2605.2002.00376.x

11. Schulster M, Bernie AM, Ramasamy R. The role of estradiol in male reproductive function. Asian J Androl. 2016;18(3):435–440. doi:10.4103/1008-682X.173932.

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    The role of estradiol in male reproductive function

    The article titled “The role of estradiol in male reproductive function” by Schulster M, Bernie AM, and Ramasamy R was published in the Asian Journal of Andrology in 2016. This article likely discusses the role of estradiol (a type of estrogen) in male reproductive function. It may cover various aspects of how estradiol influences different aspects of male reproductive physiology, including spermatogenesis, testicular function, and hormonal regulation. The goal is to provide insights into the significance of estradiol in male fertility and reproductive health. For more in-depth information and a comprehensive understanding of the topic, you can access the full article in the Asian Journal of Andrology, Volume 18, Issue 3, pages 435–440, published in 2016, via academic databases, libraries, or the journal’s website using the provided DOI: 10.4103/1008-682X.173932.

    For more details visit at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854098/

12. Rochira V, Madeo B, Diazzi C, et al. Estrogens and male reproduction. [Updated 2016 Nov 24]. In: Feingold KR, Anawalt B, Boyce A, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK278933/.

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    Estrogens and male reproduction

    The source you’ve mentioned is a chapter titled “Estrogens and male reproduction” from the book “Endotext.” This chapter is likely to provide an extensive overview of the role of estrogens in male reproductive physiology and health. It may cover topics such as the synthesis of estrogens in males, the effects of estrogens on testicular function, spermatogenesis, and other aspects of male reproductive biology.

    You can access the full article at https://www.ncbi.nlm.nih.gov/books/NBK278933/

13. Hess RA. Estrogen in the adult male reproductive tract: a review. Reprod Biol Endocrinol. 2003;1:52. Published 2003 Jul 9. doi:10.1186/1477-7827-1-52.

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    Estrogen in the adult male reproductive tract: a review. Reprod Biol Endocrinol

    The review article titled “Estrogen in the adult male reproductive tract: a review” by Hess RA was published in Reproductive Biology and Endocrinology in 2003. This review likely provides a comprehensive overview of the presence and functions of estrogen in the adult male reproductive system. It may cover topics such as the sources of estrogen in males, the role of estrogen receptors, and the physiological and regulatory functions of estrogen in the male reproductive tract.

    You can access the full article at https://link.springer.com/article/10.1186/1477-7827-1-52

14. El-Sakka AI. Impact of the association between elevated oestradiol and low testosterone levels on erectile dysfunction severity. Asian J Androl. 2013;15(4):492–496. doi:10.1038/aja.2013.20.

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    Impact of the association between elevated oestradiol and low testosterone levels on erectile dysfunction severity

    The citation you’ve provided refers to a scientific paper by El-Sakka AI, titled “Impact of the association between elevated oestradiol and low testosterone levels on erectile dysfunction severity,” published in the Asian Journal of Andrology in 2013. This study appears to explore the relationship between hormone levels, specifically elevated oestradiol and low testosterone, and the severity of erectile dysfunction.

    You can access the full article at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739229/

15. Sharpe RM. Do males rely on female hormones. Nature. 1997;390:447–8.

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    Do males rely on female hormones

    The reference you’ve provided is to a paper by Sharpe RM, titled “Do males rely on female hormones?” published in the journal Nature in 1997. This paper likely discusses the role of hormones typically associated with females, such as estrogen, in male physiology or reproductive health.

    You can access the full article at https://www.nature.com/articles/37236

16. Cohen PG. The role of estradiol in the maintenance of secondary hypogonadism in males in erectile dysfunction. Med Hypotheses. 1998;50:331–3.

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    The role of estradiol in the maintenance of secondary hypogonadism in males in erectile dysfunction

    The reference you provided is to a scientific paper by Cohen PG, titled “The Role of Estradiol in the Maintenance of Secondary Hypogonadism in Males in Erectile Dysfunction,” published in the journal Medical Hypotheses in 1998. This paper seems to discuss the influence of estradiol, a form of estrogen, in maintaining secondary hypogonadism in males, particularly in the context of erectile dysfunction.

    You can access the full article at https://www.sciencedirect.com/science/article/pii/S0306987798900068

17. Srilatha B, Adaikan PG. Oestrogen–androgen crosstalk in the pathophysiology of erectile dysfunction. Asian J Androl. 2003;5:307–13.

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    Oestrogen–androgen crosstalk in the pathophysiology of erectile dysfunction.

    The reference you’ve provided is for a scientific paper titled “Oestrogen–androgen crosstalk in the pathophysiology of erectile dysfunction,” authored by Srilatha B and Adaikan PG, and published in the Asian Journal of Andrology in 2003. This research appears to focus on how estrogen and androgen hormones interact and influence the pathophysiology of erectile dysfunction.

    You can access the full article at https://europepmc.org/article/med/14695981

18. Srilatha B, Adaikan PG, Chong YS. Relevance of oestradiol testosterone balance in erectile dysfunction patients’ prognosis. Singapore Med J. 2007;48:114–8.

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    Relevance of oestradiol testosterone balance in erectile dysfunction patients’ prognosis

    The reference you’ve provided is to a scientific paper titled “Relevance of oestradiol testosterone balance in erectile dysfunction patients’ prognosis,” authored by Srilatha B, Adaikan PG, and Chong YS, published in the Singapore Medical Journal in 2007. This study seems to investigate the significance of the balance between oestradiol (a form of estrogen) and testosterone levels in predicting the prognosis of patients with erectile dysfunction.

    You can access the full article at http://www.smj.org.sg/sites/default/files/4802/4802a1.pdf

19. El-Sakka AI, Hassoba HM. Age-related testosterone depletion in patients with erectile dysfunction. J Urol. 2006;176:2589–93.

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    Age-related testosterone depletion in patients with erectile dysfunction.

    The reference you mentioned is to a scientific paper titled “Age-related testosterone depletion in patients with erectile dysfunction,” authored by El-Sakka AI and Hassoba HM, and published in the Journal of Urology in 2006. This study likely examines the relationship between aging, testosterone levels, and the incidence or severity of erectile dysfunction.

    You can access the full article at https://www.sciencedirect.com/science/article/pii/S002253470601977X

20. Wu F, Chen T, Mao S, Jiang H, Ding Q, Xu G. Levels of estradiol and testosterone are altered in Chinese men with sexual dysfunction. Andrology. 2016;4(5):932-8.

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    Levels of estradiol and testosterone are altered in Chinese men with sexual dysfunction

    The reference you’ve provided is to a scientific paper titled “Levels of estradiol and testosterone are altered in Chinese men with sexual dysfunction,” authored by Wu F, Chen T, Mao S, Jiang H, Ding Q, Xu G, and published in the journal Andrology in 2016. This research likely investigates the changes in hormone levels, specifically estradiol and testosterone, in Chinese men experiencing sexual dysfunction.

    You can access the full article at https://onlinelibrary.wiley.com/doi/abs/10.1111/andr.12195

21. Srilatha B, Adaikan PG. Endocrine milieu and erectile dysfunction: is oestradiol-testosterone imbalance, a risk factor in the elderly?. Asian J Androl. 2011;13(4):569–573. doi:10.1038/aja.2010.129.

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    Endocrine milieu and erectile dysfunction: is oestradiol-testosterone imbalance, a risk factor in the elderly?

    The reference you’ve provided points to a scientific paper titled “Endocrine milieu and erectile dysfunction: is oestradiol-testosterone imbalance, a risk factor in the elderly?” by Srilatha B and Adaikan PG, published in the Asian Journal of Andrology in 2011. This study likely explores the potential role of an imbalance between oestradiol (a form of estrogen) and testosterone levels as a risk factor for erectile dysfunction in elderly men.

    You can access the full article at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739617/

22. Lafranchi SH, Parlow AF, Lippe BM, Coyotupa J, Kaplan SA. Pubertal gynecomastia and transient elevation of serum estradiol level. Am J Dis Child. 1975;129(8):927-31.

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    Pubertal gynecomastia and transient elevation of serum estradiol level

    The citation you provided refers to a scientific paper titled “Pubertal Gynecomastia and Transient Elevation of Serum Estradiol Level,” authored by Lafranchi SH, Parlow AF, Lippe BM, Coyotupa J, and Kaplan SA, published in the American Journal of Diseases of Children in 1975. This study seems to focus on the occurrence of gynecomastia (enlargement of breast tissue) in pubertal males, potentially in relation to temporary increases in serum estradiol (a form of estrogen) levels.

    You can access the full article at https://jamanetwork.com/journals/jamapediatrics/article-abstract/506122

23. Braunstein GD. Aromatase and gynecomastia. Endocr Relat Cancer. 1999;6(2):315-24.

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    Aromatase and gynecomastia. Endocr Relat Cancer

    The reference you’ve provided is to a scientific paper titled “Aromatase and Gynecomastia,” authored by Braunstein GD, published in Endocrine-Related Cancer in 1999. This paper likely discusses the role of aromatase, an enzyme responsible for the conversion of androgens to estrogens, in the development of gynecomastia, which is the enlargement of breast tissue in males.

    You can access the full article at https://erc.bioscientifica.com/view/journals/erc/6/2/10731125.xml

24. Cuhaci N, Polat SB, Evranos B, Ersoy R, Cakir B. Gynecomastia: Clinical evaluation and management. Indian J Endocrinol Metab. 2014;18(2):150-8.

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    Clinical evaluation and management. Indian J Endocrinol Metab

    The reference you mentioned is to a scientific paper titled “Gynecomastia: Clinical evaluation and management,” authored by Cuhaci N, Polat SB, Evranos B, Ersoy R, and Cakir B, published in the Indian Journal of Endocrinology and Metabolism in 2014. This paper likely covers various aspects of gynecomastia, including its clinical evaluation, diagnosis, and management strategies.

    You can access the full article at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987263/

25. Swerdloff RS, Ng CM. Gynecomastia: Etiology, Diagnosis, and Treatment. 2019 Jul 7. In: Feingold KR, Anawalt B, Boyce A, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK279105/.

    View Summary +

    Gynecomastia: etiology, diagnosis, and treatment

    The reference you’ve provided is for a chapter titled “Gynecomastia: Etiology, Diagnosis, and Treatment,” authored by Swerdloff RS and Ng CM, included in the book “Endotext,” edited by Feingold KR, Anawalt B, Boyce A, et al. This chapter, available online and published on July 7, 2019, is part of a comprehensive endocrinology resource. It likely covers the causes, diagnostic procedures, and treatment options for gynecomastia, which is the enlargement of breast tissue in males.

    You can access the full article at https://www.ncbi.nlm.nih.gov/sites/books/NBK279105/

26. Cuhaci N, Polat SB, Evranos B, Ersoy R, Cakir B. Gynecomastia: Clinical evaluation and management. Indian J Endocrinol Metab. 2014;18(2):150–158. doi:10.4103/2230-8210.129104.

    View Summary +

    Clinical evaluation and management

    The reference you provided is to a scientific article titled “Gynecomastia: Clinical Evaluation and Management,” authored by Cuhaci N, Polat SB, Evranos B, Ersoy R, and Cakir B. It was published in the Indian Journal of Endocrinology and Metabolism in 2014. This paper likely explores various aspects of gynecomastia, including how it is clinically evaluated and managed.

    You can access the full article at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3987263/

27. Johnson RE, Murad MH. Gynecomastia: pathophysiology, evaluation, and management. Mayo Clin Proc. 2009;84(11):1010–1015. doi:10.1016/S0025-6196(11)60671-X.

    View Summary +

    Gynecomastia: pathophysiology, evaluation, and management

    The reference you provided is to a scientific paper titled “Gynecomastia: Pathophysiology, Evaluation, and Management,” authored by Johnson RE and Murad MH, published in the Mayo Clinic Proceedings in 2009. This article likely offers a comprehensive overview of gynecomastia, including its pathophysiology (the functional changes that accompany the disease), methods for clinical evaluation and diagnosis, and various management strategies.

    You can access the full article at https://www.sciencedirect.com/science/article/pii/S002561961160671X

28. Lemaine V, Cayci C, Simmons PS, Petty P. Gynecomastia in adolescent males. Semin Plast Surg. 2013;27(1):56–61. doi:10.1055/s-0033-1347166.

    View Summary +

    Gynecomastia in adolescent males

    The citation you’ve provided refers to a scientific paper titled “Gynecomastia in Adolescent Males,” authored by Lemaine V, Cayci C, Simmons PS, and Petty P, published in the journal Seminars in Plastic Surgery in 2013. This article likely focuses on the occurrence, evaluation, and management of gynecomastia specifically in adolescent males, a period when this condition is relatively common due to the hormonal changes associated with puberty.

    You can access the full article at https://www.thieme-connect.com/products/ejournals/html/10.1055/s-0033-1347166

29. Narula HS, Carlson HE. Gynaecomastia–pathophysiology, diagnosis and treatment. Nat Rev Endocrinol. 2014;10(11):684-98.

    View Summary +

    Gynaecomastia—pathophysiology, diagnosis and treatment

    The reference you’ve provided is to a scientific paper titled “Gynaecomastia–Pathophysiology, Diagnosis and Treatment,” authored by Narula HS and Carlson HE, published in Nature Reviews Endocrinology in 2014. This article likely provides an in-depth review of gynecomastia, covering aspects such as its pathophysiological mechanisms, diagnostic approaches, and therapeutic options.

    You can access the full article at https://www.nature.com/articles/nrendo.2014.139

30. Johnson RE, Kermott CA, Murad MH. Gynecomastia – evaluation and current treatment options. Ther Clin Risk Manag. 2011;7:145–148. doi:10.2147/TCRM.S10181.

    View Summary +

    Gynecomastia–evaluation and current treatment options

    The reference you’ve provided is to a scientific paper titled “Gynecomastia – Evaluation and Current Treatment Options,” authored by Johnson RE, Kermott CA, and Murad MH. It was published in the journal Therapeutics and Clinical Risk Management in 2011. This paper likely discusses the methods for evaluating gynecomastia, a condition characterized by the enlargement of breast tissue in males, as well as the contemporary treatment options available for managing this condition.

    You can access the full article at https://www.tandfonline.com/doi/abs/10.2147/TCRM.S10181

31. Edidin DV, Levitsky LL. Prepubertal gynecomastia associated with estrogen-containing hair cream. Am J Dis Child. 1982;136(7):587-8.

    View Summary +

    Prepubertal gynecomastia associated with estrogen-containing hair cream

    The reference you mentioned is to a scientific paper titled “Prepubertal Gynecomastia Associated with Estrogen-Containing Hair Cream,” authored by Edidin DV and Levitsky LL. This paper was published in the American Journal of Diseases of Children in 1982. The study seems to explore a unique case or cases of prepubertal gynecomastia (enlargement of breast tissue in boys before puberty) and its possible association with the use of an estrogen-containing hair cream.

    You can access the full article at https://jamanetwork.com/journals/jamapediatrics/article-abstract/510522

32. Goldman RD. Drug-induced gynecomastia in children and adolescents. Can Fam Physician. 2010;56(4):344–345.

    View Summary +

    Drug-induced gynecomastia in children and adolescents

    The reference you provided is to a scientific paper titled “Drug-induced Gynecomastia in Children and Adolescents,” authored by Goldman RD, published in the Canadian Family Physician journal in 2010. This paper likely discusses cases of gynecomastia (the enlargement of breast tissue in males) in children and adolescents that are induced by certain medications.

    You can access the full article at https://www.cfp.ca/content/56/4/344?eaf=

33. de Ronde W, de Jong FH. Aromatase inhibitors in men: effects and therapeutic options. Reprod Biol Endocrinol. 2011;9:93. Published 2011 Jun 21. doi:10.1186/1477-7827-9-93.

    View Summary +

    Aromatase inhibitors in men: effects and therapeutic options

    The reference you’ve provided is to a scientific paper titled “Aromatase Inhibitors in Men: Effects and Therapeutic Options,” authored by de Ronde W and de Jong FH. It was published in the journal Reproductive Biology and Endocrinology in 2011. This article likely examines the effects of aromatase inhibitors in men and discusses their potential therapeutic uses. Aromatase inhibitors are drugs that reduce estrogen production and are commonly used in the treatment of estrogen-sensitive cancers, but they may also have applications in treating conditions related to estrogen activity in men.

    You can access the full article at https://rbej.biomedcentral.com/articles/10.1186/1477-7827-9-93

34. Schneider G, Kirschner MA, Berkowitz R, Ertel NH. Increased estrogen production in obese men. J Clin Endocrinol Metab. 1979;48(4):633-8.

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    Increased estrogen production in obese men

    The reference you mentioned is to a scientific paper titled “Increased Estrogen Production in Obese Men,” authored by Schneider G, Kirschner MA, Berkowitz R, and Ertel NH. This study was published in the Journal of Clinical Endocrinology and Metabolism in 1979. It likely investigates the relationship between obesity and increased estrogen production in men. Given the publication date, this research might have been among the earlier studies to explore the endocrine changes associated with obesity in males.

    You can access the full article at https://academic.oup.com/jcem/article-abstract/48/4/633/2678987

35. Wu A, Shi Z, Martin S, Vincent A, Heilbronn L, Wittert G. Age-related changes in estradiol and longitudinal associations with fat mass in men. PLoS ONE. 2018;13(8):e0201912.

    View Summary +

    Age-related changes in estradiol and longitudinal associations with fat mass in men

    The reference you provided is to a scientific paper titled “Age-related Changes in Estradiol and Longitudinal Associations with Fat Mass in Men,” authored by Wu A, Shi Z, Martin S, Vincent A, Heilbronn L, Wittert G. It was published in PLoS ONE in 2018. This study likely examines how levels of estradiol, a form of estrogen, change with age in men and explores the relationship between these hormonal changes and variations in body fat composition.

    You can access the full article at https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0201912

36. Zumoff B. Relationship of obesity to blood estrogens. Cancer Res. 1982;42(8 Suppl):3289s-3294s.

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    Relationship of obesity to blood estrogens

    The reference you’ve provided is to a scientific paper titled “Relationship of Obesity to Blood Estrogens,” authored by Zumoff B. It was published in the journal Cancer Research in 1982, specifically in a supplement issue. This paper likely explores the connection between obesity and the levels of estrogen in the blood. Considering the publication’s focus on cancer research, the study might also discuss the implications of this relationship in the context of cancer risk or development.

    You can access the full article at https://aacrjournals.org/cancerres/article-abstract/42/8_Supplement/3289s/486953

37. Rubinow KB. Estrogens and Body Weight Regulation in Men. Adv Exp Med Biol. 2017;1043:285–313. doi:10.1007/978-3-319-70178-3_14.

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    Estrogens and Body Weight Regulation in Men

    The reference you provided is to a chapter titled “Estrogens and Body Weight Regulation in Men,” authored by Rubinow KB, included in the book “Advances in Experimental Medicine and Biology,” published in 2017. The chapter appears to focus on the role of estrogens, a group of female sex hormones, in regulating body weight and related metabolic functions in men.

    This chapter likely offers a comprehensive overview of the current understanding of how estrogens influence body weight, fat distribution, and metabolic health in the male population. It might also discuss the mechanisms through which estrogens exert these effects and their implications for health and disease.

    You can access the full article at https://link.springer.com/chapter/10.1007/978-3-319-70178-3_14

38. Williams GP. The role of oestrogen in the pathogenesis of obesity, type 2 diabetes, breast cancer and prostate disease. Eur J Cancer Prev. 2010;19(4):256-71.

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    The role of oestrogen in the pathogenesis of obesity, type 2 diabetes, breast cancer and prostate disease

    The reference you mentioned is to a scientific paper titled “The Role of Oestrogen in the Pathogenesis of Obesity, Type 2 Diabetes, Breast Cancer, and Prostate Disease,” authored by Williams GP. It was published in the European Journal of Cancer Prevention in 2010. This paper likely examines the influence of oestrogen (estrogen) in the development and progression of several significant health conditions, including obesity, type 2 diabetes, breast cancer, and prostate disease.

    You can access the full article at https://www.jstor.org/stable/48503973

39. Kirschner MA, Ertel N, Schneider G. Obesity, hormones, and cancer. Cancer Res. 1981;41(9 Pt 2):3711-7.

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    Obesity, hormones, and cancer

    The reference you provided is to a scientific paper titled “Obesity, Hormones, and Cancer,” authored by Kirschner MA, Ertel N, and Schneider G. It was published in the journal Cancer Research in 1981. This study likely explores the interrelationships between obesity, hormonal changes, and the risk or progression of various types of cancer.

    Given the publication’s focus on cancer research, the paper might discuss how obesity-induced hormonal alterations, such as changes in estrogen or insulin levels, can influence the development or prognosis of certain cancers.

    You can access the full article at https://aacrjournals.org/cancerres/article-abstract/41/9_Part_2/3711/485913

     

40. Krieg M, Nass R, Tunn S. Effect of aging on endogenous level of 5 alpha-dihydrotestosterone, testosterone, estradiol, and estrone in epithelium and stroma of normal and hyperplastic human prostate. J Clin Endocrinol Metab. 1993 Aug;77(2):375-81.

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    Effect of aging on endogenous level of 5 alpha-dihydrotestosterone, testosterone, estradiol, and estrone in epithelium and stroma of normal and hyperplastic human prostate

    The reference you’ve provided is to a scientific paper titled “Effect of Aging on Endogenous Level of 5 Alpha-Dihydrotestosterone, Testosterone, Estradiol, and Estrone in Epithelium and Stroma of Normal and Hyperplastic Human Prostate,” authored by Krieg M, Nass R, and Tunn S. It was published in the Journal of Clinical Endocrinology and Metabolism in August 1993. This study likely investigates how aging affects the levels of various hormones, including 5 alpha-dihydrotestosterone, testosterone, estradiol, and estrone, in the prostate tissue, both in normal conditions and in cases of benign prostatic hyperplasia.

    You can access the full article at https://academic.oup.com/jcem/article-abstract/77/2/375/2650327

41. Gann PH, Hennekens CH, Longcope C, Verhoek-Oftedahl W, Grodstein F, Stampfer MJ. A prospective study of plasma hormone levels, nonhormonal factors, and development of benign prostatic hyperplasia. Prostate. 1995 Jan;26(1):40-9.

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    A prospective study of plasma hormone levels, nonhormonal factors, and development of benign prostatic hyperplasia.

    The reference you mentioned is to a scientific paper titled “A Prospective Study of Plasma Hormone Levels, Nonhormonal Factors, and Development of Benign Prostatic Hyperplasia,” authored by Gann PH, Hennekens CH, Longcope C, Verhoek-Oftedahl W, Grodstein F, Stampfer MJ. It was published in the journal Prostate in January 1995. This study likely focuses on a longitudinal analysis of how various hormonal levels and non-hormonal factors might influence the development of benign prostatic hyperplasia (BPH), a common condition involving the enlargement of the prostate gland in men.

    You can access the full article at https://onlinelibrary.wiley.com/doi/abs/10.1002/pros.2990260109

42. Shibata Y, Ito K, Suzuki K, et al. Changes in the endocrine environment of the human prostate transition zone with aging: simultaneous quantitative analysis of prostatic sex steroids and comparison with human prostatic histological composition. Prostate. 2000 Jan;42(1):45-55.

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    Changes in the endocrine environment of the human prostate transition zone with aging: simultaneous quantitative analysis of prostatic sex steroids and comparison with human prostatic histological composition

    The reference you provided is to a scientific paper titled “Changes in the Endocrine Environment of the Human Prostate Transition Zone with Aging: Simultaneous Quantitative Analysis of Prostatic Sex Steroids and Comparison with Human Prostatic Histological Composition,” authored by Shibata Y, Ito K, Suzuki K, et al. This study was published in the journal Prostate in January 2000. The research likely explores how the hormonal environment within the transition zone of the human prostate changes with age. It seems to focus on quantitatively analyzing the levels of various sex steroids in the prostate and comparing these levels with the histological (tissue) composition of the prostate.

    You can access the full article at https://onlinelibrary.wiley.com/doi/abs/10.1002/(SICI)1097-0045(20000101)42:1%3C45::AID-PROS6%3E3.0.CO;2-W

43. Prins GS, Huang L, Birch L, Pu Y. The role of estrogens in normal and abnormal development of the prostate gland. Ann N Y Acad Sci. 2006 Nov;1089:1-13.

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    The role of estrogens in normal and abnormal development of the prostate gland

    The reference you provided is to a scientific paper titled “The Role of Estrogens in Normal and Abnormal Development of the Prostate Gland,” authored by Prins GS, Huang L, Birch L, and Pu Y. It was published in the Annals of the New York Academy of Sciences in November 2006. This paper likely discusses the impact of estrogen hormones on the development of the prostate gland under normal and pathological conditions.

    The study might explore how estrogens contribute to the normal developmental processes of the prostate and how they might be implicated in disorders of the prostate, such as benign prostatic hyperplasia or prostate cancer.

    You can access the full article at https://nyaspubs.onlinelibrary.wiley.com/doi/abs/10.1196/annals.1386.009

44. Prins GS, Korach KS. The role of estrogens and estrogen receptors in normal prostate growth and disease. Steroids. 2008 Mar;73(3):233-44.

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    The role of estrogens and estrogen receptors in normal prostate growth and disease.

    The reference you’ve provided is to a scientific paper titled “The Role of Estrogens and Estrogen Receptors in Normal Prostate Growth and Disease,” authored by Prins GS and Korach KS. It was published in the journal Steroids in March 2008. This paper likely examines the influence of estrogens and their receptors on the normal growth of the prostate gland, as well as their role in prostate-related diseases.

    The study might discuss the mechanisms through which estrogen and estrogen receptors contribute to the physiological development of the prostate, and how alterations in these pathways might lead to conditions such as benign prostatic hyperplasia or prostate cancer.

    You can access the full article at https://www.sciencedirect.com/science/article/pii/S0039128X07002103

45. Matsuda T, Abe H, Suda K. Relation between benign prostatic hyperplasia and obesity and estrogen. Rinsho Byori. 2004 Apr;52(4):291-4.

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    Relation between benign prostatic hyperplasia and obesity and estrogen

    The reference you provided is to a scientific paper titled “Relation between Benign Prostatic Hyperplasia and Obesity and Estrogen,” authored by Matsuda T, Abe H, and Suda K. It was published in Rinsho Byori (The Japanese Journal of Clinical Pathology) in April 2004. This study likely investigates the association between benign prostatic hyperplasia (BPH), a common condition involving the enlargement of the prostate gland, and factors such as obesity and estrogen levels.

    The research might explore how obesity and altered estrogen levels contribute to the development or progression of BPH, potentially providing insights into hormonal influences on prostate health.

    You can access the full article at https://europepmc.org/article/med/15164594

46. Ho CK, Nanda J, Chapman KE, Habib FK. Oestrogen and benign prostatic hyperplasia: effects on stromal cell proliferation and local formation from androgen. J Endocrinol. 2008 Jun;197(3):483-91.

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    Oestrogen and benign prostatic hyperplasia

    The reference you provided is to a scientific paper titled “Oestrogen and Benign Prostatic Hyperplasia: Effects on Stromal Cell Proliferation and Local Formation from Androgen,” authored by Ho CK, Nanda J, Chapman KE, and Habib FK. It was published in the Journal of Endocrinology in June 2008. This study likely investigates the effects of estrogen on stromal cell proliferation within the prostate and how it influences the local conversion of androgens (male hormones) in the context of benign prostatic hyperplasia (BPH), a common condition characterized by the enlargement of the prostate gland.

    You can access the full article at https://joe.bioscientifica.com/view/journals/joe/197/3/483.xml

47. Singh PB, Matanhelia SS, Martin FL. A potential paradox in prostate adenocarcinoma progression: oestrogen as the initiating driver. Eur J Cancer. 2008 May;44(7):928-36.

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    A potential paradox in prostate adenocarcinoma progression: oestrogen as the initiating driver.

    The reference you’ve provided is to a scientific paper titled “A Potential Paradox in Prostate Adenocarcinoma Progression: Oestrogen as the Initiating Driver,” authored by Singh PB, Matanhelia SS, and Martin FL. It was published in the European Journal of Cancer in May 2008. This study appears to explore a somewhat unconventional hypothesis in prostate cancer research, suggesting that estrogen, typically considered a female hormone, might play an initiating role in the progression of prostate adenocarcinoma, a common type of prostate cancer.

    The paper likely discusses the mechanisms through which estrogen could potentially influence the initiation and progression of prostate cancer, challenging the traditional focus on androgens (male hormones) as the primary hormonal drivers in prostate cancer development.

    You can access the full article at https://www.sciencedirect.com/science/article/pii/S0959804908001755

48. Giton F, de la Taille A, Allory Y, et al. Estrone sulfate (E1S), a prognosis marker for tumor aggressiveness in prostate cancer (PCa). J Steroid Biochem Mol Biol. 2008 Mar;109(1-2):158-67.

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    Estrone sulfate (E1S), a prognosis marker for tumor aggressiveness in prostate cancer (PCa).

    The reference you mentioned is to a scientific paper titled “Estrone Sulfate (E1S), a Prognosis Marker for Tumor Aggressiveness in Prostate Cancer (PCa),” authored by Giton F, de la Taille A, Allory Y, et al. It was published in the Journal of Steroid Biochemistry and Molecular Biology in March 2008. This study likely investigates the potential role of estrone sulfate (E1S), a form of estrogen, as a biomarker for assessing the aggressiveness of prostate cancer.

    The research probably focuses on examining the levels of E1S in prostate cancer patients and correlating these levels with the aggressiveness of the cancer, possibly providing insights into how estrogen metabolism might be involved in the progression of prostate cancer and its potential use in prognosis.

    You can access the full article at https://www.sciencedirect.com/science/article/pii/S0960076008000289

49. Katznelson L, et al. Increase in bone density and lean body mass during testosterone administration in men with acquired hypogonadism. J. Clin. Endocrinol. Metab. 1996;81:4358–4365.

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    Increase in bone density and lean body mass during testosterone administration in men with acquired hypogonadism

    The reference you provided is to a scientific paper titled “Increase in Bone Density and Lean Body Mass during Testosterone Administration in Men with Acquired Hypogonadism,” authored by Katznelson L, et al. It was published in the Journal of Clinical Endocrinology and Metabolism in 1996. This study likely investigates the effects of testosterone therapy on bone density and lean body mass in men who have acquired hypogonadism, a condition characterized by the insufficient production of testosterone.

    The paper probably discusses how testosterone supplementation can influence body composition and bone health in men with this hormonal deficiency, exploring the potential benefits of hormone replacement therapy in managing the symptoms and health risks associated with hypogonadism.

    You can access the full article at https://academic.oup.com/jcem/article-abstract/81/12/4358/2650656

50. Colmou A. Estrogens and vascular thrombosis. Soins Gynecol Obstet Pueric Pediatr. 1982 Sep;(16):39-41.

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    Estrogens and vascular thrombosis. Soins Gynecol Obstet Pueric Pediatr

    The reference you provided is to a scientific article titled “Estrogens and Vascular Thrombosis,” authored by Colmou A. It was published in the journal Soins Gynecol Obstet Pueric Pediatr in September 1982. This article likely explores the relationship between estrogen levels or estrogen therapy and the risk of vascular thrombosis, which is the formation of blood clots within blood vessels.

    Given the publication’s focus, it might discuss the implications of estrogen therapy, such as hormone replacement therapy or contraceptive use, on the risk of thrombotic events, particularly in women.

    You can access the full article at https://pubmed.ncbi.nlm.nih.gov/6925385/

51. Danie01010ll HW. Osteoporosis after orchiectomy for prostate cancer. J. Urol. 1997;157:439–444. 01010.

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    Osteoporosis after orchiectomy for prostate cancer

    The reference you’ve provided is to a scientific paper titled “Osteoporosis after Orchiectomy for Prostate Cancer,” authored by Daniell HW. It was published in the Journal of Urology in 1997. This study likely investigates the incidence of osteoporosis in men who have undergone orchiectomy (surgical removal of one or both testicles) as a treatment for prostate cancer.

    Orchiectomy, as a form of androgen deprivation therapy, can lead to significant hormonal changes that may affect bone density. The paper probably discusses the risk factors, prevalence, and potential management strategies for osteoporosis in patients who have undergone this procedure.

    You can access the full article at https://www.auajournals.org/doi/abs/10.1016/S0022-5347%2801%2965165-6

52. Tivesten A, Hulthe J, Wallenfeldt K, et al. Circulating estradiol is an independent predictor of progression of carotid artery intima-media thickness in middle-aged men. J Clin Endocrinol Metab. 2006 Nov;91(11):4433-7.

    View Summary +

    Circulating estradiol is an independent predictor of progression of carotid artery intima-media thickness in middle-aged men

    The reference you’ve provided is to a scientific paper titled “Circulating Estradiol is an Independent Predictor of Progression of Carotid Artery Intima-Media Thickness in Middle-Aged Men,” authored by Tivesten A, Hulthe J, Wallenfeldt K, et al. It was published in the Journal of Clinical Endocrinology and Metabolism in November 2006. This study likely examines the relationship between levels of estradiol, a form of estrogen, and the progression of atherosclerosis as measured by the thickness of the intima-media layer in the carotid arteries in middle-aged men.

    The paper probably explores how estradiol levels might be linked to cardiovascular risk, particularly focusing on the development of arterial plaque which is an indicator of atherosclerosis.

    You can access the full article at https://academic.oup.com/jcem/article-abstract/91/11/4433/2656585

53. Mohamad MJ, Mohammad MA, Karayyem M, Hairi A, Hader AA. Serum levels of sex hormones in men with acute myocardial infarction. Neuro Endocrinol Lett. 2007 Apr;28(2):182-6.

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    Serum levels of sex hormones in men with acute myocardial infarction

    The reference you provided is to a scientific paper titled “Serum Levels of Sex Hormones in Men with Acute Myocardial Infarction,” authored by Mohamad MJ, Mohammad MA, Karayyem M, Hairi A, Hader AA. It was published in the Neuro Endocrinology Letters in April 2007. This study likely investigates the serum (blood) levels of various sex hormones in men who have experienced an acute myocardial infarction (AMI), commonly known as a heart attack.

    The research probably focuses on assessing the levels of hormones like testosterone, estradiol, and possibly others, in the context of acute cardiac events. The aim could be to explore potential correlations or associations between sex hormone levels and the risk or severity of myocardial infarction.

    You can access the full article at https://www.nel.edu/userfiles/articlesnew/NEL280207A13.pdf

54. Dunajska K, Milewicz A, Szymczak J, et al. Evaluation of sex hormone levels and some metabolic factors in men with coronary atherosclerosis. Aging Male. 2004 Sep;7(3):197-204.

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    Evaluation of sex hormone levels and some metabolic factors in men with coronary atherosclerosis

    The reference you’ve provided is to a scientific paper titled “Evaluation of Sex Hormone Levels and Some Metabolic Factors in Men with Coronary Atherosclerosis,” authored by Dunajska K, Milewicz A, Szymczak J, et al. It was published in the journal Aging Male in September 2004. This study likely focuses on assessing the levels of various sex hormones, along with certain metabolic factors, in men who have been diagnosed with coronary atherosclerosis, a condition characterized by the buildup of plaque in the coronary arteries.

    The paper probably examines the relationship between hormones like testosterone and estrogen, and factors such as lipid profiles, glucose levels, and other metabolic indicators, in the context of heart disease in men. The goal might be to understand how these hormonal and metabolic factors are interconnected and contribute to the development or progression of coronary atherosclerosis.

    You can access the full article at https://www.tandfonline.com/doi/abs/10.1080/13685530400004181

55. Tivesten A, Mellstrom D, Jutberger H, et al. Low serum testosterone and high serum estradiol associate with lower extremity peripheral arterial disease in elderly men. The MrOS Study in Sweden. J Am Coll Cardiol. 2007 Sep 11;50(11):1070-6.

    View Summary +

    Low serum testosterone and high serum estradiol associate with lower extremity peripheral arterial disease in elderly men.

    The reference you provided is to a scientific paper titled “Low Serum Testosterone and High Serum Estradiol Associate with Lower Extremity Peripheral Arterial Disease in Elderly Men. The MrOS Study in Sweden,” authored by Tivesten A, Mellstrom D, Jutberger H, et al. It was published in the Journal of the American College of Cardiology (JACC) on September 11, 2007. This study likely investigates the relationship between hormone levels, specifically low serum testosterone and high serum estradiol, and the occurrence of lower extremity peripheral arterial disease (PAD) in elderly men.

    The research probably explores how hormonal factors, including imbalances in testosterone and estradiol, may be associated with the development or progression of PAD, which is a condition characterized by the narrowing of arteries in the legs.

    You can access the full article at https://www.jacc.org/doi/abs/10.1016/j.jacc.2007.04.088

56. Tengstrand B, Carlstrom K, Fellander-Tsai L, Hafstrom I. Abnormal levels of serum dehydroepiandrosterone, estrone, and estradiol in men with rheumatoid arthritis: high correlation between serum estradiol and current degree of inflammation. J Rheumatol. 2003 Nov;30(11):2338-43.

    View Summary +

    Abnormal levels of serum dehydroepiandrosterone, estrone, and estradiol in men with rheumatoid arthritis

    The reference you provided is to a scientific paper titled “Abnormal Levels of Serum Dehydroepiandrosterone, Estrone, and Estradiol in Men with Rheumatoid Arthritis: High Correlation between Serum Estradiol and Current Degree of Inflammation,” authored by Tengstrand B, Carlstrom K, Fellander-Tsai L, and Hafstrom I. It was published in the Journal of Rheumatology in November 2003. This study likely investigates the serum levels of dehydroepiandrosterone (DHEA), estrone, and estradiol in men with rheumatoid arthritis and explores their correlation with the degree of inflammation associated with the disease.

    The paper probably delves into the hormonal imbalances observed in men with rheumatoid arthritis, with a particular focus on the role of estradiol and its connection to the ongoing inflammatory processes in these individuals.

    You can access the full article at https://www.jrheum.org/content/30/11/2338.short

57. Stork S, Bots ML, Grobbee DE, van der Schouw YT. Endogenous sex hormones and C-reactive protein in healthy postmenopausal women. J Intern Med. 2008 Mar 12.

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    Endogenous sex hormones and C-reactive protein in healthy postmenopausal women

    The reference you provided is to a scientific paper titled “Endogenous Sex Hormones and C-reactive Protein in Healthy Postmenopausal Women,” authored by Stork S, Bots ML, Grobbee DE, and van der Schouw YT. Although the publication date is not included, the paper likely discusses the relationship between endogenous sex hormones (hormones produced within the body) and C-reactive protein (CRP) levels in healthy postmenopausal women.

    CRP is a marker of inflammation, and this study probably investigates how sex hormone levels, such as estrogen and testosterone, are associated with inflammation in postmenopausal women. Understanding this relationship can have implications for assessing cardiovascular risk and overall health in this population.

    You can access the full article at https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-2796.2008.01946.x

58. Zegura B, Guzic-Salobir B, Sebestjen M, Keber I. The effect of various menopausal hormone therapies on markers of inflammation, coagulation, fibrinolysis, lipids, and lipoproteins in healthy postmenopausal women. Menopause. 2006 Jul;13(4):643-50.

    View Summary +

    The effect of various menopausal hormone therapies on markers of inflammation, coagulation, fibrinolysis, lipids, and lipoproteins in healthy postmenopausal women

    The reference you provided is to a scientific paper titled “The Effect of Various Menopausal Hormone Therapies on Markers of Inflammation, Coagulation, Fibrinolysis, Lipids, and Lipoproteins in Healthy Postmenopausal Women,” authored by Zegura B, Guzic-Salobir B, Sebestjen M, and Keber I. It was published in the journal Menopause in July 2006. This study likely investigates the impact of different menopausal hormone therapies (such as hormone replacement therapy) on various health markers in healthy postmenopausal women.

    The research probably assesses how these hormone therapies affect markers of inflammation, coagulation (blood clotting), fibrinolysis (breaking down of blood clots), as well as lipid and lipoprotein profiles. Understanding these effects is important for evaluating the potential benefits and risks associated with menopausal hormone therapy.

    You can access the full article at https://journals.lww.com/menopausejournal/Fulltext/2006/13040/The_effect_of_various_menopausal_hormone_therapies.15.aspx

59. Hemelaar M, Kenemans P, Schalkwijk CG, Braat DD, van der Mooren MJ. No increase in C-reactive protein levels during intranasal compared to oral hormone therapy in healthy post-menopausal women. Hum Reprod. 2006 Jun;21(6):1635-42.

    View Summary +

    No increase in C-reactive protein levels during intranasal compared to oral hormone therapy in healthy post-menopausal women

    The reference you provided is to a scientific paper titled “No Increase in C-reactive Protein Levels during Intranasal Compared to Oral Hormone Therapy in Healthy Post-menopausal Women,” authored by Hemelaar M, Kenemans P, Schalkwijk CG, Braat DD, and van der Mooren MJ. It was published in Human Reproduction in June 2006. This study likely investigates the impact of different hormone therapy administration methods (intranasal vs. oral) on C-reactive protein (CRP) levels in healthy post-menopausal women.

    CRP is a marker of inflammation, and the research likely assesses whether there is a difference in CRP levels when hormone therapy is administered through different routes, such as intranasal or oral. Understanding this can be important in evaluating the potential inflammatory effects of hormone therapy in postmenopausal women.

    You can access the full article at https://academic.oup.com/humrep/article-abstract/21/6/1635/724486

60. Abbott RD, Launer LJ, Rodriguez BL, et al. Serum estradiol and risk of stroke in elderly men. Neurology. 2007 Feb 20;68(8):563-8.

    View Summary +

    Serum estradiol and risk of stroke in elderly men

    The reference you provided is to a scientific paper titled “Serum Estradiol and Risk of Stroke in Elderly Men,” authored by Abbott RD, Launer LJ, Rodriguez BL, et al. It was published in Neurology on February 20, 2007. This study likely investigates the relationship between serum estradiol levels and the risk of stroke in elderly men.

    The research probably explores whether there is an association between the levels of estradiol, a form of estrogen, and the incidence of stroke in older men. Understanding this relationship can have implications for assessing the hormonal factors that may contribute to stroke risk in the elderly population.

    You can access the full article at https://n.neurology.org/content/68/8/563.short

61. Falahati-Nini A, et al. Relative contributions of testosterone and estrogen in regulating bone resorption and formation in normal elderly men. J. Clin. Invest. 2000;106:1553–1560.

    View Summary +

    Relative contributions of testosterone and estrogen in regulating bone resorption and formation in normal elderly men

    The reference you provided is to a scientific paper titled “Relative Contributions of Testosterone and Estrogen in Regulating Bone Resorption and Formation in Normal Elderly Men,” authored by Falahati-Nini A and colleagues. It was published in the Journal of Clinical Investigation in 2000. This study likely investigates the roles of testosterone and estrogen in the regulation of bone resorption (the breakdown of bone tissue) and bone formation in healthy elderly men.

    The research probably delves into how both testosterone and estrogen, two important sex hormones, influence bone health in aging men. It may examine their relative contributions to maintaining bone density and preventing bone loss.

    For more details visit https://www.jci.org/articles/view/10942

62. Cauley JA. Estrogen and bone health in men and women. Steroids. 2015; 99(Pt A):11-5.

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    Estrogen and bone health in men and women

    The reference you provided is to a scientific paper titled “Estrogen and Bone Health in Men and Women,” authored by Jane A. Cauley. It was published in the journal Steroids in 2015. This paper likely discusses the role of estrogen in maintaining bone health in both men and women.

    Estrogen is a hormone that plays a crucial role in bone metabolism, and this paper may explore how estrogen influences bone density, bone formation, and the prevention of bone loss in both genders. It may also discuss the effects of estrogen deficiency on bone health and the potential benefits of hormone therapy in managing bone-related conditions.

    For more details visit https://www.sciencedirect.com/science/article/pii/S0039128X14003031

63. Carlsen CG, Soerensen TH, Eriksen EF. Prevalence of low serum estradiol levels in male osteoporosis. Osteoporosis international: a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 2000; 11(8):697-701.

    View Summary +

    Prevalence of low serum estradiol levels in male osteoporosis

    The reference you provided is to a scientific paper titled “Prevalence of Low Serum Estradiol Levels in Male Osteoporosis,” authored by Carlsen CG, Soerensen TH, and Eriksen EF. It was published in Osteoporosis International in 2000. This study likely investigates the prevalence of low serum estradiol levels in men with osteoporosis.

    Osteoporosis is a condition characterized by reduced bone density and increased bone fragility, and estrogen (including estradiol) plays a role in bone health. This research may examine the relationship between low estradiol levels and the occurrence of osteoporosis in men.

    For more details visit https://search.proquest.com/openview/b66226fdbd4525dbdc7e9c83c4a6d535/1?pq-origsite=gscholar&cbl=33762

64. Mosekilde L, Vestergaard P, Rejnmark L. The pathogenesis, treatment and prevention of osteoporosis in men. Drugs. 2013; 73(1):15-29.

    View Summary +

    The pathogenesis, treatment and prevention of osteoporosis in men

    The reference you provided is to a scientific paper titled “The Pathogenesis, Treatment, and Prevention of Osteoporosis in Men,” authored by Mosekilde L, Vestergaard P, and Rejnmark L. It was published in the journal Drugs in 2013. This paper likely provides an overview of the pathogenesis (the process of development), treatment, and prevention of osteoporosis in men.

    Osteoporosis is a condition characterized by reduced bone density and increased bone fragility, and it is typically associated with postmenopausal women. However, this paper appears to focus on osteoporosis in men, which is less common but still important to understand.

    For more details visit https://link.springer.com/article/10.1007/s40265-012-0003-1

65. Ebeling PR. Idiopathic or hypogonadal osteoporosis in men: current and future treatment options. Treatments in endocrinology. 2004; 3(6):381-91.

    View Summary +

    Idiopathic or hypogonadal osteoporosis in men: current and future treatment options

    The reference you provided is to a scientific paper titled “Idiopathic or Hypogonadal Osteoporosis in Men: Current and Future Treatment Options,” authored by Ebeling PR. It was published in Treatments in Endocrinology in 2004. This paper likely discusses the current and potential future treatment options for idiopathic (of unknown cause) or hypogonadal (related to low gonadal function, typically low testosterone) osteoporosis in men.

    Osteoporosis is a condition characterized by reduced bone density and increased bone fragility, and it can affect both men and women. This paper may explore the various treatment approaches available at the time of publication and may also speculate on future developments in the field.

    For more details visit https://link.springer.com/article/10.2165/00024677-200403060-00006

66. Banu J. Causes, consequences, and treatment of osteoporosis in men. Drug Des Devel Ther. 2013;7:849–860. Published 2013 Aug 22. doi:10.2147/DDDT.S46101.

    View Summary +

    Causes, consequences, and treatment of osteoporosis in men

    The reference you provided is to a scientific paper titled “Causes, Consequences, and Treatment of Osteoporosis in Men,” authored by Banu J. It was published in Drug Design, Development and Therapy in 2013. This paper likely discusses the causes, consequences, and treatment options for osteoporosis in men.

    Osteoporosis is a condition characterized by reduced bone density and increased bone fragility, and it can affect both men and women. This paper may provide insights into the factors that contribute to osteoporosis in men, its consequences for their health, and the available treatment strategies.

    For more details visit https://www.tandfonline.com/doi/full/10.2147/DDDT.S46101

67. Ebeling PR. Osteoporosis in men. New insights into aetiology, pathogenesis, prevention and management. Drugs & aging. 1998; 13(6):421-34.

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    New insights into aetiology, pathogenesis, prevention and management

    The reference you provided is to a scientific paper titled “Osteoporosis in Men: New Insights into Aetiology, Pathogenesis, Prevention, and Management,” authored by Ebeling PR. It was published in Drugs & Aging in 1998. This paper likely provides insights into the understanding of osteoporosis in men, including its causes, development, prevention, and management.

    Osteoporosis is a condition characterized by reduced bone density and increased bone fragility, and it can affect both men and women. This paper may have contributed to the knowledge of osteoporosis in men by discussing the factors contributing to the condition, its pathogenesis, and approaches to prevention and management.

    For more details visit https://link.springer.com/article/10.2165/00002512-199813060-00002

68. Manolagas SC, O’Brien CA, Almeida M. The role of estrogen and androgen receptors in bone health and disease. Nat Rev Endocrinol. 2013;9(12):699–712. doi:10.1038/nrendo.2013.179.

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    The role of estrogen and androgen receptors in bone health and disease

    The reference you provided is to a scientific review article titled “The Role of Estrogen and Androgen Receptors in Bone Health and Disease,” authored by Manolagas SC, O’Brien CA, and Almeida M. It was published in Nature Reviews Endocrinology in 2013. This review likely explores the roles of estrogen and androgen receptors in maintaining bone health and their involvement in bone-related diseases.

    Estrogen and androgen receptors play crucial roles in bone metabolism, and this review may delve into the mechanisms through which these hormones affect bone tissue. It may also discuss how dysregulation of these receptors can lead to bone-related conditions such as osteoporosis.

    For more details visit https://www.nature.com/articles/nrendo.2013.179.pdf

69. Legrand E, Hedde C, Gallois Y, et al. Osteoporosis in men: a potential role for the sex hormone binding globulin. Bone. 2001; 29(1):90-5.

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    Osteoporosis in men: a potential role for the sex hormone binding globulin

    The reference you provided is to a scientific paper titled “Osteoporosis in Men: A Potential Role for the Sex Hormone Binding Globulin,” authored by Legrand E, Hedde C, Gallois Y, et al. It was published in the journal Bone in 2001. This paper likely explores the potential role of sex hormone binding globulin (SHBG) in osteoporosis in men.

    Sex hormone binding globulin (SHBG) is a glycoprotein that binds to sex hormones such as testosterone and estradiol, regulating their availability in the bloodstream. This paper may investigate how SHBG levels or activity could impact bone health in men, including its potential role in the development of osteoporosis.

    For more details visit https://www.sciencedirect.com/science/article/pii/S8756328201004781

70. Khosla S, Amin S, Orwoll E. Osteoporosis in men. Endocr Rev. 2008;29(4):441–464. doi:10.1210/er.2008-0002.

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    Osteoporosis in men

    The reference you provided is to a scientific review article titled “Osteoporosis in Men,” authored by Khosla S, Amin S, and Orwoll E. It was published in Endocrine Reviews in 2008. This comprehensive review likely provides an extensive overview of osteoporosis in men, including its causes, diagnosis, management, and the latest research in the field.

    Osteoporosis is a condition characterized by reduced bone density and increased bone fragility, and it affects both men and women. This review article may cover a wide range of topics related to osteoporosis in men, including its epidemiology, risk factors, pathophysiology, and treatment options.

    For more details visit https://academic.oup.com/edrv/article-abstract/29/4/441/2355012

71. Adler RA. Osteoporosis in men: a review. Bone Res. 2014;2:14001. Published 2014 Apr 29. doi:10.1038/boneres.2014.1.

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    Osteoporosis in men: a review

    The reference you provided is to a review article titled “Osteoporosis in Men: A Review,” authored by Adler RA. It was published in Bone Research in 2014. This review likely provides an overview of osteoporosis in men, summarizing key aspects of the condition.

    Osteoporosis in men is a condition characterized by reduced bone density and increased bone fragility, and it is less common than in women but still important to understand and manage. This review article may cover various aspects of osteoporosis in men, including its epidemiology, risk factors, diagnosis, and management.

    For more details visit https://www.nature.com/articles/boneres20141

72. Khosla S, Melton LJ, Riggs BL. Estrogens and bone health in men. Calcified tissue international. 2001; 69(4):189-92.

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    Estrogens and bone health in men

    The reference you provided is to a scientific paper titled “Estrogens and Bone Health in Men,” authored by Khosla S, Melton LJ, and Riggs BL. It was published in Calcified Tissue International in 2001. This paper likely discusses the role of estrogens in maintaining bone health in men.

    Estrogens are typically associated with female reproductive health, but they also play a role in bone metabolism in both men and women. This paper may explore how estrogens contribute to bone health in men and how changes in estrogen levels can impact bone density and strength.

    For more details visit https://search.ebscohost.com/login.aspx?direct=true&profile=ehost&scope=site&authtype=crawler&jrnl=0171967X&asa=Y&AN=15246961&h=%2BgEVccmSGrxy4dirNze4wJde4PCH0nQv1aJD0SNhKeCA6I7RPGSn35TTYsTsfD9GGSfaK%2BlPecR%2FiEB5v0dFmA%3D%3D&crl=c

73. Misiorowski W. Osteoporosis in men. Prz Menopauzalny. 2017;16(2):70–73. doi:10.5114/pm.2017.68596.

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    Osteoporosis in men

    The reference you provided is to a scientific paper titled “Osteoporosis in Men,” authored by Misiorowski W. It was published in Przeglad Menopauzalny (Menopause Review) in 2017. This paper likely discusses osteoporosis in men, including its prevalence, risk factors, diagnosis, and management.

    Osteoporosis is a condition characterized by reduced bone density and increased bone fragility, and it can affect both men and women, although it is more common in women. This paper may provide insights into the specific aspects of osteoporosis in men and may offer recommendations for its prevention and treatment.

    For more details visit https://www.termedia.pl/Osteoporosis-in-men,4,30166,0,1.html

74. Falahati-Nini A, Riggs BL, Atkinson EJ, O’Fallon WM, Eastell R, Khosla S. Relative contributions of testosterone and estrogen in regulating bone resorption and formation in normal elderly men. J Clin Invest. 2000;106(12):1553–1560. doi:10.1172/JCI10942.

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    Relative contributions of testosterone and estrogen in regulating bone resorption and formation in normal elderly men

    The reference you provided is to a scientific paper titled “Relative Contributions of Testosterone and Estrogen in Regulating Bone Resorption and Formation in Normal Elderly Men,” authored by Falahati-Nini A, Riggs BL, Atkinson EJ, O’Fallon WM, Eastell R, and Khosla S. It was published in the Journal of Clinical Investigation in 2000. This paper likely explores the roles of testosterone and estrogen in regulating bone metabolism in elderly men.

    Bone health is influenced by sex hormones, including testosterone and estrogen, in both men and women. This study may have investigated how these hormones contribute to bone resorption (breakdown) and bone formation in elderly men, shedding light on the complex interplay between hormones and bone health.

    For more details visit https://www.jci.org/articles/view/10942

75. Xin HB, Senbonmatsu T, Cheng DS, et al. Oestrogen protects FKBP12.6 null mice from cardiac hypertrophy. 2002;416(6878):334-33811907581.

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    Oestrogen protects FKBP12.6 null mice from cardiac hypertrophy.

    The reference you provided is to a scientific paper titled “Estrogen Protects FKBP12.6 Null Mice from Cardiac Hypertrophy,” authored by Xin HB, Senbonmatsu T, Cheng DS, et al. It was published in the journal Nature in 2002. This paper likely investigates the protective effects of estrogen on cardiac hypertrophy in mice lacking FKBP12.6.

    Cardiac hypertrophy is a condition characterized by an enlargement of the heart muscle and can be associated with various cardiovascular diseases. Estrogen is known to have protective effects on the cardiovascular system, and this study may have explored how estrogen influences cardiac hypertrophy in the absence of FKBP12.6.

    For more details visit https://www.nature.com/articles/416334a

76. Li J, Wu M, Que L, et al. 17Beta-estradiol attenuates cardiac dysfunction and decreases NF-kappaB binding activity in mechanically stretched rat hearts. 2008;73(7):720-72618405931.

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    17β-Estradiol attenuates cardiac dysfunction and decreases NF-κB binding activity in mechanically stretched rat hearts

    The reference you provided is to a scientific paper titled “17Beta-Estradiol Attenuates Cardiac Dysfunction and Decreases NF-kappaB Binding Activity in Mechanically Stretched Rat Hearts,” authored by Li J, Wu M, Que L, et al. It was published in 2008.

    This paper likely investigates the effects of 17Beta-estradiol (a form of estrogen) on cardiac function and NF-kappaB binding activity in mechanically stretched rat hearts. Mechanical stress on the heart, as can occur in conditions like heart failure, can lead to cardiac dysfunction. Estrogen is known to have protective effects on the cardiovascular system, and this study may have explored how it influences cardiac function under conditions of mechanical stress.

    For more details visit https://www.sciencedirect.com/science/article/pii/S0039128X08000792

77. Satoh M, Matter CM, Ogita H, et al. Inhibition of apoptosis-regulated signaling kinase-1 and prevention of congestive heart failure by estrogen. 2007;115(25):3197-320417562954.

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    Inhibition of apoptosis-regulated signaling kinase-1 and prevention of congestive heart failure by estrogen

    The reference you provided is to a scientific paper titled “Inhibition of Apoptosis-Regulated Signaling Kinase-1 and Prevention of Congestive Heart Failure by Estrogen,” authored by Satoh M, Matter CM, Ogita H, et al. It was published in 2007.

    This paper likely explores the role of estrogen in inhibiting apoptosis-regulated signaling kinase-1 (ASK1) and its potential preventive effects on congestive heart failure. Congestive heart failure is a condition where the heart is unable to pump blood effectively, and ASK1 is a kinase involved in cellular signaling pathways related to apoptosis (cell death).

    Estrogen is known to have cardioprotective effects, and this study may have investigated the mechanisms by which estrogen can prevent congestive heart failure, including its interaction with ASK1.

    For more details visit https://www.ahajournals.org/doi/abs/10.1161/circulationaha.106.657981

78. Lee TM, Lin MS, Chou TF, Tsai CH, Chang NC. Adjunctive 17beta-estradiol administration reduces infarct size by altered expression of canine myocardial connexin43 protein. Cardiovasc Res. 2004;63(1):109-11715194467.

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    Adjunctive 17beta-estradiol administration reduces infarct size by altered expression of canine myocardial connexin43 protein

    The reference you provided is to a scientific paper titled “Adjunctive 17Beta-Estradiol Administration Reduces Infarct Size by Altered Expression of Canine Myocardial Connexin43 Protein,” authored by Lee TM, Lin MS, Chou TF, Tsai CH, and Chang NC. It was published in Cardiovascular Research in 2004.

    This paper likely investigates the effects of adjunctive administration of 17Beta-estradiol (a form of estrogen) on myocardial infarct size in canines. Myocardial infarction, commonly known as a heart attack, occurs when there is a lack of blood supply to a portion of the heart, leading to tissue damage. Connexin43 is a protein involved in intercellular communication within the heart.

    For more details visit https://academic.oup.com/cardiovascres/article-abstract/63/1/109/282117

79. Kadokami T, McTiernan CF, Higuichi Y, Frye CS, Kubota T, Feldman AM. 17Beta-estradiol improves survival in male mice with cardiomyopathy induced by cardiac-specific tumor necrosis factor-alpha overexpression. J Interferon Cytokine Res. 2005;25(5):254-26015871662.

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    17β-estradiol improves survival in male mice with cardiomyopathy induced by cardiac-specific tumor necrosis factor-α overexpression

    The reference you provided is to a scientific paper titled “17Beta-Estradiol Improves Survival in Male Mice with Cardiomyopathy Induced by Cardiac-Specific Tumor Necrosis Factor-Alpha Overexpression,” authored by Kadokami T, McTiernan CF, Higuichi Y, Frye CS, Kubota T, and Feldman AM. It was published in the Journal of Interferon & Cytokine Research in 2005.

    This paper likely explores the effects of 17Beta-estradiol (a form of estrogen) on the survival of male mice with cardiomyopathy induced by the overexpression of tumor necrosis factor-alpha (TNF-alpha) specifically in the heart. Cardiomyopathy refers to a disease of the heart muscle.

    For more details visit https://www.liebertpub.com/doi/abs/10.1089/jir.2005.25.254

80. Mahmoodzadeh S, Eder S, Nordmeyer J, et al. Estrogen receptor alpha up-regulation and redistribution in human heart failure. FASEB J. 2006;20(7):926-93416675850.

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    Estrogen receptor alpha up-regulation and redistribution in human heart failure.

    The reference you provided is to a scientific paper titled “Estrogen Receptor Alpha Up-Regulation and Redistribution in Human Heart Failure,” authored by Mahmoodzadeh S, Eder S, Nordmeyer J, et al. It was published in the FASEB Journal in 2006.

    This paper likely investigates the up-regulation (increased expression) and redistribution of estrogen receptor alpha (ER-alpha) in the hearts of individuals with heart failure. Estrogen receptors play a role in mediating the effects of estrogen in various tissues, including the heart.

    The study may have explored how changes in ER-alpha expression and localization are associated with heart failure and whether these changes have any implications for cardiac function.

    For more details visit https://faseb.onlinelibrary.wiley.com/doi/abs/10.1096/fj.05-5148com

81. Carani C, Qin K, Simoni M, Faustini-Fustini M, Serpente S, Boyd J, et al. Effect of testosterone and estradiol in a man with aromatase deficiency. N Engl J Med. (1997) 337:91–5. doi: 10.1056/NEJM199707103370204.

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    Effect of testosterone and estradiol in a man with aromatase deficiency

    The reference you provided is to a scientific paper titled “Effect of Testosterone and Estradiol in a Man with Aromatase Deficiency,” authored by Carani C, Qin K, Simoni M, Faustini-Fustini M, Serpente S, Boyd J, et al. It was published in the New England Journal of Medicine in 1997.

    This paper likely explores the effects of testosterone and estradiol supplementation in a man with aromatase deficiency. Aromatase is an enzyme responsible for converting androgens (like testosterone) into estrogens (like estradiol). Aromatase deficiency can lead to low estrogen levels.

    For more details visit https://www.nejm.org/doi/full/10.1056/nejm199707103370204

82. Smith EP, Boyd J, Frank GR, Takahashi H, Cohen RM, Specker B, et al. Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man. N Engl J Med. (1994) 331:1056–61. doi: 10.1056/NEJM199410203311604.

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    Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man

    The reference you provided is to a scientific paper titled “Estrogen Resistance Caused by a Mutation in the Estrogen-Receptor Gene in a Man,” authored by Smith EP, Boyd J, Frank GR, Takahashi H, Cohen RM, Specker B, et al. It was published in the New England Journal of Medicine in 1994.

    This paper likely describes a case of estrogen resistance in a man due to a mutation in the estrogen receptor gene. Estrogen receptors are proteins that mediate the effects of estrogen in the body. Mutations in these receptors can lead to reduced responsiveness to estrogen.

    For more details visit https://www.nejm.org/doi/full/10.1056/NEJM199410203311604

83. Morishima A, Grumbach MM, Simpson ER, Fisher C, Qin K. Aromatase deficiency in male and female siblings caused by a novel mutation and the physiological role of estrogens. J Clin Endocrinol Metab. (1995) 80:3689–98. doi: 10.1210/jc.80.12.3689.

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    Aromatase deficiency in male and female siblings caused by a novel mutation and the physiological role of estrogens

    The reference you provided is to a scientific paper titled “Aromatase Deficiency in Male and Female Siblings Caused by a Novel Mutation and the Physiological Role of Estrogens,” authored by Morishima A, Grumbach MM, Simpson ER, Fisher C, and Qin K. It was published in the Journal of Clinical Endocrinology & Metabolism in 1995.

    This paper likely discusses a case of aromatase deficiency in both male and female siblings due to a novel mutation. Aromatase is the enzyme responsible for converting androgens (such as testosterone) into estrogens. Aromatase deficiency can lead to low estrogen levels.

    For more details visit https://academic.oup.com/jcem/article-abstract/80/12/3689/2650081

84. Sudhir K, Chou TM, Messina LM, Hutchison SJ, Korach KS, Chatterjee K, et al. Endothelial dysfunction in a man with disruptive mutation in oestrogen-receptor gene. Lancet. (1997) 349:1146–7. doi: 10.1016/S0140-6736(05)63022-X.

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    Endothelial dysfunction in a man with disruptive mutation in oestrogen-receptor gene

    The reference you provided is to a scientific paper titled “Endothelial Dysfunction in a Man with a Disruptive Mutation in the Estrogen-Receptor Gene,” authored by Sudhir K, Chou TM, Messina LM, Hutchison SJ, Korach KS, Chatterjee K, et al. It was published in The Lancet in 1997.

    This paper likely reports a case of endothelial dysfunction in a man with a disruptive mutation in the estrogen receptor gene. Endothelial dysfunction refers to impaired function of the endothelium, the inner lining of blood vessels. Estrogen receptors play a role in endothelial function, and mutations in these receptors can have implications for cardiovascular health.

    For more details visit https://www.academia.edu/download/49572999/s0140-6736_2805_2963022-x20161013-17232-17q4oo2.pdf

85. Fink G, Sumner BE, Rosie R, Grace O, Quinn JP. Estrogen control of central neurotransmission: effect on mood, mental state, and memory. Cell Mol Neurobiol. 1996;16(3):325–44.

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    Estrogen control of central neurotransmission: effect on mood, mental state, and memory

    The reference you provided is to a scientific paper titled “Estrogen Control of Central Neurotransmission: Effect on Mood, Mental State, and Memory,” authored by Fink G, Sumner BE, Rosie R, Grace O, and Quinn JP. It was published in the journal Cellular and Molecular Neurobiology in 1996.

    This paper likely explores the role of estrogen in the regulation of central neurotransmission and its effects on mood, mental state, and memory. Estrogen is known to have neuroactive properties and can influence various aspects of brain function and behavior.

    For more details visit https://link.springer.com/article/10.1007/BF02088099

86. Kulkarni J, Gavrilidis E, Worsley R, Van Rheenen T, Hayes E. The role of estrogen in the treatment of men with schizophrenia. Int J Endocrinol Metab. 2013;11(3):129–136. doi:10.5812/ijem.6615.

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    The role of estrogen in the treatment of men with schizophrenia

    The reference you provided is to a scientific paper titled “The Role of Estrogen in the Treatment of Men with Schizophrenia,” authored by Kulkarni J, Gavrilidis E, Worsley R, Van Rheenen T, and Hayes E. It was published in the International Journal of Endocrinology and Metabolism in 2013.

    This paper likely discusses the potential therapeutic role of estrogen in the treatment of men with schizophrenia. Schizophrenia is a complex psychiatric disorder, and estrogen is known to have neuroprotective and neuromodulatory effects that may be relevant to its management.

    The study may have explored the effects of estrogen supplementation or modulation on symptoms and outcomes in male individuals with schizophrenia, and it may have discussed the underlying mechanisms through which estrogen could influence the condition.

    For more details visit https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3860106/

87. Luine VN. Estradiol and cognitive function: past, present and future. Horm Behav. 2014;66(4):602–618. doi:10.1016/j.yhbeh.2014.08.011.

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    Estradiol and cognitive function: past, present and future

    The reference you provided is to a scientific review article titled “Estradiol and Cognitive Function: Past, Present, and Future,” authored by Luine VN. It was published in the journal Hormones and Behavior in 2014.

    This review article likely discusses the relationship between estradiol (a form of estrogen) and cognitive function. Estrogen, including estradiol, plays a significant role in various aspects of cognitive function, including memory and learning. The article may provide an overview of past research on this topic, current understanding, and potential future directions in the study of estradiol’s effects on cognition.

    For more details visit https://www.sciencedirect.com/science/article/pii/S0018506X14001846

88. Dohanich GP. Gonadal steroids, learning and memory. In: Pfaff DW, Arnold AP, Etgen AM, Fahrbach SE, Rubin RI, editors. Hormones, Brain and Behavior. Academic Press; San Diego: 2002. pp. 265–327.

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    Gonadal steroids, learning and memory

    The reference you provided is from the book “Hormones, Brain and Behavior,” specifically from a chapter titled “Gonadal Steroids, Learning, and Memory,” authored by Dohanich GP. The book is edited by Pfaff DW, Arnold AP, Etgen AM, Fahrbach SE, and Rubin RI, and it was published by Academic Press.

    This chapter likely discusses the role of gonadal steroids, including sex hormones like estrogen and testosterone, in learning and memory processes. Gonadal steroids have been shown to influence cognitive function, and this chapter may provide insights into the mechanisms through which these hormones affect learning and memory.

    For more details visit https://www.sciencedirect.com/science/article/pii/B978012532104450024X

89. Luine VN, Dohanich G. Sex differences in cognitive function in Rodents. In: Becker JB, Berkley KJ, Geary N, Hampson E, Herman JP, Young E, editors. Sex Differences in the Brain: From Genes to Behavior. Oxford University Press; 2008. pp. 227–252.

    View Summary +

    Sex differences in cognitive function in Rodents

    The reference you provided is from the book “Sex Differences in the Brain: From Genes to Behavior,” specifically from a chapter titled “Sex Differences in Cognitive Function in Rodents,” authored by Luine VN and Dohanich G. The book is edited by Becker JB, Berkley KJ, Geary N, Hampson E, Herman JP, and Young E, and it was published by Oxford University Press in 2008.

    This chapter likely discusses research on sex differences in cognitive function in rodents, exploring how male and female rodents may differ in terms of learning and memory processes. Understanding these differences can provide insights into the role of sex hormones and genetics in cognitive function.

90. Bagatell CJ, Knopp RH, Rivier JE, Bremner WJ. Physiological levels of estradiol stimulate plasma high density lipoprotein2 cholesterol levels in normal men. J Clin Endocrinol Metab. 1994;78(4):855-61.

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    Physiological levels of estradiol stimulate plasma high density lipoprotein2 cholesterol levels in normal men

    The study “Physiological levels of estradiol stimulate plasma high density lipoprotein2 cholesterol levels in normal men” by Bagatell CJ, Knopp RH, Rivier JE, and Bremner WJ, published in the Journal of Clinical Endocrinology and Metabolism in 1994, explores the role of estradiol in regulating lipid levels in men. The research was conducted in response to the observation that premenopausal women have a lower risk of coronary artery disease than men or postmenopausal women, with estrogens believed to contribute to this lower risk.

    For more details visit https://pubmed.ncbi.nlm.nih.gov/8157711/

91. Jankowska EA, Rozentryt P, Ponikowska B. Circulating estradiol and mortality in men with systolic chronic heart failure. JAMA. 2009 May 13;301(18):1892-901.

    View Summary +

    Circulating estradiol and mortality in men with systolic chronic heart failure

    The study “Circulating Estradiol and Mortality in Men with Systolic Chronic Heart Failure,” published in JAMA in 2009 by Jankowska EA, Rozentryt P, Ponikowska B, et al., examined the relationship between serum estradiol levels and mortality in men with chronic heart failure and reduced left ventricular ejection fraction (LVEF). It was a prospective observational study of 501 men with chronic heart failure. The main finding was that both high and low concentrations of estradiol, compared to the middle quintile, were associated with increased mortality. This study highlights the significance of estradiol levels in men with chronic heart failure, suggesting that both excessively high and low levels are linked to higher mortality rates.

    For more details visit https://pubmed.ncbi.nlm.nih.gov/19436016/

92. Tivesten A, Vandenput L, Labrie F, et al. Low serum testosterone and estradiol predict mortality in elderly men. The Journal of clinical endocrinology and metabolism. 2009; 94(7):2482-8.

    View Summary +

    Low serum testosterone and estradiol predict mortality in elderly men

    The study “Low serum testosterone and estradiol predict mortality in elderly men,” published in the Journal of Clinical Endocrinology and Metabolism in 2009, investigated the association between serum testosterone and estradiol levels and all-cause mortality in elderly men. The researchers utilized gas chromatography-mass spectrometry to analyze serum sex steroids in older men participating in the MrOS Sweden cohort, which included 3014 men with an average age of 75 years.

    The main finding of the study was that low levels of both testosterone and estradiol were associated with increased mortality risk. Specifically, during a mean follow-up period of 4.5 years, there were 383 deaths among the participants. The study found that men in the lowest quartile for both testosterone and estradiol levels had a significantly higher risk of death compared to those in higher quartiles. The hazard ratios for low testosterone and low estradiol were 1.65 and 1.54, respectively. Furthermore, the risk of death nearly doubled in subjects with low levels of both hormones compared to those with levels in the higher quartiles.

    For more details visit https://academic.oup.com/jcem/article/94/7/2482/2597039

93. Jankowska EA, Rozentryt P, Ponikowska B, et al. Circulating estradiol and mortality in men with systolic chronic heart failure. JAMA. 2009 May 13;301(18):1892-901.

    View Summary +

    Circulating estradiol and mortality in men with systolic chronic heart failure.

    The study “Circulating Estradiol and Mortality in Men with Systolic Chronic Heart Failure,” published in JAMA in 2009 by Jankowska EA, Rozentryt P, Ponikowska B, et al., examined the relationship between serum estradiol levels and mortality in men with chronic heart failure and reduced left ventricular ejection fraction (LVEF). It was a prospective observational study of 501 men with chronic heart failure. The main finding was that both high and low concentrations of estradiol, compared to the middle quintile, were associated with increased mortality. This study highlights the significance of estradiol levels in men with chronic heart failure, suggesting that both excessively high and low levels are linked to higher mortality rates.

    For more details visit https://pubmed.ncbi.nlm.nih.gov/19436016/

     

94. Finkelstein JS, Lee H, Burnett-Bowie SA, et al. Gonadal steroids and body composition, strength, and sexual function in men. N Engl J Med. 2013 Sep 12;369(11):1011-22.

    View Summary +

    Gonadal steroids and body composition, strength, and sexual function in men.

    The study “Gonadal Steroids and Body Composition, Strength, and Sexual Function in Men,” published in the New England Journal of Medicine in 2013 by Finkelstein JS, Lee H, Burnett-Bowie SA, et al., investigated the effects of varying levels of testosterone and estradiol on body composition, strength, and sexual function in men. The study found that the amount of testosterone required to maintain lean mass, fat mass, strength, and sexual function varied widely among men.

    Key findings from the study included that androgen deficiency was primarily responsible for decreases in lean mass, muscle size, and strength. On the other hand, estrogen deficiency primarily accounted for increases in body fat. Moreover, both deficiencies contributed to a decline in sexual function. These results suggest the importance of considering both testosterone and estradiol levels in the evaluation and management of hypogonadism in men.

    For more details visit https://pubmed.ncbi.nlm.nih.gov/24024838/